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New ALS Gene and Signaling Pathways Identified

Findings point to potential therapeutic targets

Toxin from Brain Cells Triggers Neuron Loss in Human ALS Model

Study in Human Cells May Improve Ability to Identify Useful Drug Targets

Motor Neuron Center


Columbia’s Motor Neuron Center will transform our understanding of human health. For the first time, brilliant scientific minds are working together in a common approach to currently incurable motor neuron diseases: spinal muscular atrophy (SMA) in children and amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease) in adults. New discoveries in the field of motor neuron biology will fuel the search for effective therapy for patients.